Established in 1987, the San Antonio Geriatric Research, Education and Clinical Center (GRECC) serves elderly Veterans in central and south Texas. Its current research interests include: metabolic and inflammatory disorders in advancing age; metabolic disease management; frailty; cognitive/sensory impairment; oral health in the elderly; end of life care; and health care utilization and quality assessment.
The mission of the San Antonio Geriatric Research, Education and Clinical Center (GRECC) is to be a center of excellence for the advancement of research, education, and clinical care in geriatrics and gerontology. Through the commitment, motivation, creativity, and dedication from all the people who are part of the GRECC, and affiliated institutions and centers, we strive to improve the life of older Veterans that served our Country. Faculty and staff working at the GRECC are dedicated to realizing the vision of a world where older Veterans live a long and enjoyable life.
The San Antonio GRECC activities center on the broad themes of metabolism and inflammation. These activities are aimed at gaining new knowledge about the basic biology of aging, mechanisms regulating longevity, and understanding the pathophysiology of numerous age-related diseases that affect the lives of millions of older Veterans, including diabetes, obesity, sarcopenia, Alzheimer’s disease, heart failure, and Parkinson’s disease.
Dr. Nicolas Musi is a Physician-Scientist who received clinical training in Internal Medicine at the University of Miami-Jackson Memorial Medical Center. Dr. Musi then completed a clinical and research fellowship in Endocrinology and Metabolism at the Joslin Diabetes Center-Beth Israel Deaconess Medical Center and Harvard Medical School in 2001 after which he joined the Harvard faculty. Recruited to The University of Texas Health Science Center at San Antonio (UTHSCSA) * in 2003, he served as Associate Director for clinical research at the Texas Diabetes Institute and is a member of the Barshop Institute for Longevity and Aging Studies *. Upon being named Director of the GRECC in 2010, Dr. Musi was also appointed Director of the newly established UTHSCSA Medical School’s Center for Healthy Aging *.
Dr. Musi’s research expertise is in aging, insulin resistance and exercise physiology. Dr. Musi has a robust research program in metabolic/endocrine gerontology, devoted to exploring the effects that aging has on numerous metabolic and cellular processes, and relevant to the patho-genesis of age-related diseases such as diabetes, obesity, and sarcopenia. He is principal investigator on two National Institutes of Health R01 (project) grants and a grant from the American Diabetes Association. Dr. Musi is the recipient of a Paul B. Beeson Career Development Award in Aging Research, co-sponsored by the National Institute on Aging (NIA) and the American Federation for Aging Research. An active educator and research mentor, he supervises clinical and research fellows, residents, and graduate students. Dr. Musi’s main clinical interests are (i) pathogenesis, prevention and treatment of diabetes in the elderly; (ii) molecular mechanisms underlying sarcopenia of aging; and (iii) effects of exercise on glucose and lipid metabolism at the whole-body and cellular levels.
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